CYTOPLASMIC OVEREXPRESSION OF CD95L IN ESOPHAGEAL ADENOCARCINOMA CELLS OVERCOMES RESISTANCE TO CD95-MEDIATED APOPTOSIS

Cytoplasmic Overexpression of CD95L in Esophageal Adenocarcinoma Cells Overcomes Resistance to CD95-Mediated Apoptosis

Introduction: The CD95/CD95L pathway plays a critical role in tissue homeostasis and immune system regulation; however, the function of this pathway in malignancy remains poorly understood.We hypothesized that CD95L expression in esophageal adenocarcinoma confers advantages to the neoplasm other than immune privilege.Methods: CD95L expression was c

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